ISBN-10:
0471950521
ISBN-13:
9780471950523
Pub. Date:
09/28/1994
Publisher:
Wiley
Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology / Edition 1

Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology / Edition 1

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Overview

Contains essential facts and concepts spanning many of the important drug classes. Features an authoritative section on general methodology and regulatory issues. The molecular biology and pharmacology of key receptor types are considered along with the detailed pharmacodynamics of a wide range of therapeutic drug groups.

Product Details

ISBN-13: 9780471950523
Publisher: Wiley
Publication date: 09/28/1994
Pages: 508
Product dimensions: 6.30(w) x 9.33(h) x 1.34(d)

About the Author

Neal R. Cutler is the editor of Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology, published by Wiley. John J. Sramek is the editor of Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology, published by Wiley.

Table of Contents

Partial table of contents:

OVERVIEW OF PHARMACODYNAMICS.

Basic Pharmacodynamic Concepts and Models (R. Wills).

Factors Influencing Variability in Kinetics and Dynamics (P. Narang& R. Li).

General Perspectives on the Role of Metabolite in Pharmacokineticsand Pharmacodynamics (R. Seifert).

Regulatory Perspective: The Role of Pharmacokinetics andPharmacodynamics (L. Lesko & R. Williams).

APPLICATION OF PHARMACODYNAMICS IN SELECTED THERAPEUTICDOMAINS.

Theoretical Models for Developing Anxiolytics (P. Nickell & T.Uhde).

Pharmacodynamics of Antipsychotic Drugs in Schizophrenia (J. Sramek& G. Simpson).

Antihypertensive Drugs (L. Prisant & A. Carr).

Pharmacodynamics of Antineoplastic Agents (G. Rosner & M.Ratain).

Virology and Antiviral Drug Development (M. Amantea, et al.).

FRONTIERS IN PHARMACODYNAMICS: INSIGHT FROM MOLECULARAPPROACHES.

Muscarinic Receptors: Pharmacological Subtypes, Structure, Functionand Regulation (L. Mei, et al.).

Serotonin Receptor Subtypes (D. Pritchett).

Index.

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