Alzheimer's Disease: Optimizing Drug Development Strategies

Alzheimer's Disease: Optimizing Drug Development Strategies


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Both prescriptive and descriptive, this outstanding guide directs readers toward improved drug development strategies in Alzheimer's disease. Profiles the importance of designing clinical trial protocols that ensure adequate evaluation of the efficacy and safety of potential pharmacological treatments.

Product Details

ISBN-13: 9780471951452
Publisher: Wiley
Publication date: 09/27/1994
Pages: 178
Product dimensions: 6.24(w) x 9.33(h) x 0.59(d)

Table of Contents

Alzheimer's Disease: The Problem and the Search for Solutions.

Diagnosis: Procedures and Criteria.

Basic and Clinical Alzheimer's Disease Models.

Central End-Organ Responses: Structural and Functional Measures.

Peripheral End-Organ Responses: Red Blood Cell Cholinesterase and Salivary Amylase.

Neuropsychological End-Organ Responses: The Computerized Neuropsychological Test Battery.

Subject Selection and Sample Size.

Age as a Factor in Drug Development.

Finding the Dose: The Bridging Study.

Concluding Remarks.


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